Dr.Kumar Pati

Dr. Abhay Kumar Pati is dedicated in promoting Biotechayur, a green company and it's subsidiaries/affiliates in Orissa, India to develop and market green technologies, products and services for improving healthcare, agriculture, nutrition and environment.

Dr. Abhay Kumar Pati was born in Raj-Nilgiri, Balasore District, Orissa, India. Dr. Pati was trained as a Physician in Calcutta at J.B. Ray State Ayurvedic Medical College & Hospital [Asthanga Ayurvedic College], which is one of the oldest Ayurvedic institutions in India, under Calcutta University. Dr. Pati came to U.S.A. almost 30 years (3 decades) ago on a fellowship. He was the publisher of an International Health Magazine called Health World. Dr. Pati is an author of several health books including, Vitamins and Herbal Digest, a 360 page book, which has been printed more than 7 times and sold over 800,000 copies in the world’s market. In this digest, readers can find nutritional, Ayurvedic, Chinese, Native American, South American herbal supplements and much, much more.

Lutein^TM :

A registered trademark of Best Nutrition Products Inc, USA.

500 mg (60 capsules)

Price : $9.95

POSTAGE WILL BE CALCULATED
for DOMESTIC AND INTERNATIONAL

 

Lutein^TMTMTM (pronounced  as  LOO-teen).

Lutein^TM is a carotenoid, meaning a natural colorant or pigment, available in green leafy vegetables such as spinach, fruits and corn. 

Lutein^TM is also found in egg yolk.

Lutein^TM provides nutritional support to our eyes and skin, the only organs of the body directly exposed to the outside environment.

Lutein^TM has been linked to promoting healthy eyes through reducing the risk of macular degeneration.

Lutein^TM: important in our diet:

Lutein^TM is an antioxidant that appears to quench or reduce harmful free radicals in various parts of the  body.

Lutein^TM: How much do we need

Research indicates a minimum of 6 – 10mg per day of Lutein^TM from green leafy vegetables and other sources is  necessary to realize Lutein^TM’s health benefits. Spinach contains a good percent of Lutein^TM.

Lutein^TM and Age related Macular Degeneration (AMD)

Research has suggested a minimum of 6-10 mg per day of Lutein^TM is necessary to realize Lutein^TM’s health benefits.  One such benefit is Lutein^TM’s role in eye health, specifically its role in reducing the risk of Age Related Macular Degeneration (AMD).

AMD occurs when the fragile center of the retina-the macula-deteriorates from a lifetime of slow but steady damage.  The macula is a small area of the retina responsible for entral vision, and high visual acuity. Poor macular health can cause oxidative stress within the retina, leading to a loss of central vision.

According to AMD alliance International dry AMD, the more common and milder form of AMD, accounts for 85% to 90% of all cases.  It develops gradually over time and usually causes only mild loss of vision.  One key identifier for AMD is the collection of small, round , white-yellow, fatty deposits called drusen in the central part of the retina.  Drusen accumulate in the  Retinal Pigment Epithelium (RPE) tissue beneath the macula and the macula thins and dries out.  The amount of vision loss is related to the location and amount of macular thinning caused by the drusen.  Sometimes abnormal new blood vessels form (wet AMD).  It is therefore important for individuals with dry AMD to have their eyes examined regularly, because it may eventually develop into the wet form.

Although the wet form of AMD accounts for only 10 – 15% of all AMD, the chance for severe sight loss is much greater.  It is responsible for 90% of severe vision loss associated with AMD.  Wet AMD is caused by the growth of  abnormal blood vessels, or choroidal nevascularization (CNV), under the central part of the retina, the macula.  These abnormal vessels leak fluid and blood into the tissue at the back of the eye, causing a blister to form in the retina.  This progression leads to scar tissue, distortion and a loss of central vision.  Wet AMD can rapidly damage the macula and result in a very quick loss of central vision.

Lutein^TM and its related compound zeaxanthin are highly concentrated in the macula, providing a yellow color known as the macular pigment (MP).  The macular pigment protects the macula from the damaging photo-oxidative effects of blue light.

Of the 600 or so carotenoids present in nature, only a handful are present in human serum.  Of  those, nature has chosen only Lutein^TM and zeaxanthin to be present in the macula.  These facts alone suggest that Lutein^TM plays a critical role in eye health.

There is a wealth of data available supporting a role for Lutein^TM in reducing the risk of AMD. There are a number of observational studies showing the association between Lutein^TM intake, serum levels, macular pigment density (MPD).

Controlled intervention studies in humans are needed to establish causality.  In terms of eye health, more and more studies investigating the direct effect of dietary Lutein^TM and Lutein^TM supplementation on macular pigment density are now being published.

Researchers agree that it is the body of evidence that must be evaluated collectively in order to determine the merits of a given nutrient, and any conclusions based on a single study are premature.  The body of evidence appears to support a beneficial role for Lutein^TM in eye health.

Lutein^TM is a yellow pigment in the chemical family of carotenoids and produced by vegetables, marigold flowers, alfalfa and to a lesser degree in many other plants.  The original medical association of Lutein^TM was as an isolate from the corpus luteum, a part of the ovaries, and hence its name (Latin for egg yolk), but an important medical aspect is its presence in the macula of the eye where it is strongly implicated in maintaining eye health.  Humans do not synthesize Lutein^TM and depend entirely on dietary sources such as vegetables or supplement Lutein^TM pills.

Lutein^TM – See Why Lutein^TM is So Important

Lutein^TM is naturally found in healthy eyes, and since it is not made in the boy, it must be obtained from dietary sources.  Research indicates that Lutein^TM  may act as a filter to protect the central area of the eye’s retina, cassed the macula, from potentially damaging forms of light.  Lutein^TM nutritionally promotes and maintains eye health.  It also possesses antioxidant capabilities.

Lutein^TM is a member of the carotenoid family, a group of naturally occurring fat-soluble pigments found in plants.  Lutein^TM is the principal carotenoid present in the macula.  The macula is responsible for supporting the health of the eye’s photoreceptor cell layer, which is why carotenoid levels are so important.

LUTEIN^TM RESEARCH – BLINDED STUDY WITH VISIBLE RESULTS

Lutein^TM has been shown to be beneficial to longterm visual health.  Seventeen participants were randomized in a double-blind study involving dietary supplementation with Lutein^TM (15 mg), alpha-tocopherol (100 mg), or placebo, three times a week for up to two years.  Visual performance, acuity and glare sensitivity were measured as parameters of vision health.  In all parameters measured, subjects that consumed the Lutein^TM had significant improvements in vision health when compared to the other groups.

In another recent placebo-controlled study, Lutein^TM resulted in a significant improvement in eye pigment and optical density when compared to the placebo.  The Lutein^TM groups also significantly improved their visual acuity when compared to placebo.

LUTEIN^TM BENEFITS

Lutein^TM possesses antioxidant capabilities
Lutein^TM may act as a filter for the central area of the retins
Lutein^TM promotes and maintains eye health

THE STORY BEHIND LUTEIN^TM

Lutein^TM is an important natural antioxidant that may help your eyes stay healthy while maintaining the health of your skin

WHERE TO FIND LUTEIN^TM

Lutein^TM is found naturally in foods such as dark green leafy vegetables and egg yolks.  Other Lutein^TM sources include vitamins and dietary supplements, as well as certain processed foods.

LUTEIN^TM

Lutein^TM (LOO-teen) (from atin lutea meaning “yellow”) is one of over 600 known naturally occurring carotenoids.  Found in green leafy vegetables such as spinach and kale, Lutein^TM is employed by organisms as an antioxidant and for blue light absorption.  Lutein^TM is covalently bound to one or more fatty acids present in some fruits and flowers, notable marigolds (Tagetes).  Saponificantion of Lutein^TM esters yields Lutein^TM in approximately a 2:1 weight-to-weight conversion.  Lutein^TM is also found in egg yolks, animal fats and the corpus luteum.

Lutein^TM is a lipophilic molecule and is generally insoluble in water.  The presence of the long chromophore of conjugated double bonds (polyene chain) provides the distinctive light-absorbing properties.  The polyene chain is susceptible to oxidative degradation by light or heat and is chemically unstable in acids.

AS A PIGMENT  

This xanthophylls, like its sister compound zeaxanthin, has primarily been used as a natural colorant due to its orange-red color.  Lutein^TM absorbs blue light and therefore appears yellow at low concentrations and orange-red at high concentrations.

Lutein^TM was traditionally used in chicken feed to provide the yellow color of broiler chicken skin.  Polled consumers viewed yellow chicken skin more favorably than white chicken skin.  Such Lutein^TM fortification also results in a darker yellow egg yolk.  Today the coloring of the egg yolk has become the primary reason for feed fortification.  Lutein^TM is not used as a colorant in other foods due to its limited stability, especially in the presence of other dyes.

ROLE IN HUMAN EYES

Lutein^TM was found to be present in a concentrated area of the macula, a small area of the retina responsible for central vision.  The  hypothesis for the natural concentration is that Lutein^TM helps protect from oxidative stress and high-energy light.  Various research studies have shown that a direct relationship exists between Lutein^TM intake and pigmentation in the eye. Several studies also show that an increase in macula pigmentation decreases the risk for eye diseases such as Age-related Macular Degeneration (AMD).  The only randomized clinical trial to demonstrate a benefit for Lutein^TM in Macular Degeneration was a small study, in which the authors concluded that more study was needed. 

Lutein^TM is a natural part of human diet when fruits and vegetables are consumed.  For individuals lacking sufficient Lutein^TM intake, Lutein^TM-fortified foods are available, or in the case of elderly people with a poorly absorbing digestive system, a sublingual spray is available.  As early as 1996, Lutein^TM has been incorporated into dietary supplements.  While no recommended daily allowance currently exists for Lutein^TM as for other nutrients, positive effects have been seen at dietary intake levels of 6 mg/day.  The only definitive side effect of excess Lutein^TM consumption is bronzing of the skin (carotenodermia). The functional difference between Lutein^TM (free form) and Lutein^TM esters is not entirely known.  It is suggested that the bioavailability is lower for Lutein^TM esters, but much debate continues.

As a food additive, Lutein^TM has the E number E161B. On September 10, 2007, in a 6-year study, researchers led by John Paul San Giovanni of the National Eye Institute, Maryland found that Lutein^TM and zeaxanthin (nutrients in eggs, spinach and other green vegetables) protect against blindness (macular degeneration), affecting 1.2 million Americans, mostly after age 65.  Lutein^TM and zeaxanthin reduce the risk of AMD (journal Archives of Ophthalmology).  Foods considered good sources of the nutrients also include kale, turnip greens, collard greens, romaine lettuce, broccoli, zucchini, corn, garden peas and Brussels sprouts.

COMMERCIAL VALUE

The Lutein^TM market is segmented into Pharmaceutical, Nutraceutical, Food, Pet Foods and Animal Feed and Fish Feed.  The Pharmaceutical market is estimated to be about US $190 Million, Nutraceutical and Food is estimated to be about US $ 175 million annually.  Apart from the customary Age related Macular Degeneration applications, newer applications are emerging in Cosmetics, Skin Care and as an Antioxidant.  It is one of the fastest growing areas of the $ 2 Billion carotenoid market.  There are several Lutein^TM ester suppliers, but few pure natural products, namely marigolds.  Companies like Indus Biotech PVt. Ltd, OmniActive Health Technologies and Kemin Industries have patents.  The market size of Lutein^TM is anticipated to grow at an average annual growth rate of over 22%.